Study title

SLT for PACG Multi-centre Study

Type

Prospective Effect of SLT in specific subgroups of patients with glaucoma

Number of patients

15 15 30 30 30 30

Primery investigator

Ma. Cecilia Aquino  Wong Hon Tym Ho Ching Lin Mario Aquino Prin Rojanapongpun Jimmy S.M. Lai

Secondary investigators

           

Contact informaion

Hon_Tym_Wong@ttsh.com.sg

Place

National University Hospital Tan Tock Seng Hospital Singapore National Eye Centre St. Luke's Medical Center, Chulalongkorn Hospital, United Christian Hospital

Town

Singapore Singapore Singapore Manila Bangkok Hong Kong

Country

Singapore Singapore Singapore Philippines Thailand Chine

Start date

Jul-05 aug-05 Oct-05 Jul-05 Sep-05 Jul-05

Expected completion date

Jul-06 Aug-06 Aug-06 Jul-06 Sep-06 Jul-06

Expected publication date

 

Purpose

To investigate the effects of Selective Laser Trabeculoplasty (SLT) as a treatment of Primary Angle Closer glaucoma (PACG)

Method

Patients with PACG, a patent peripheral iridectomy and a clear view of at least 90 degrees of the pigmented trabecular meshwork were treated by SLT covering  all the visible meshwork

Preliminary Results

The mean baseline IOP was 24.1±2.1 mmHg. In the 42 eyes that reached one month follow up the average IOP was 19.6±2.7 mmHg (19% reduction).  At this time point there was a hypotensive response of 2 mmHg or more in all but 4 eyes (90%). At three month the average IOP in 26 eyes was 19.3±3.0 (19% reduction) and there was an IOP reduction of 2 mmHg or over in 85% of the eyes. Fifteen eyes reached 6 months follow up with an average IOP of 19.3±1.8 mmHg (20% reduction). There was a 2 mmHg reduction of 2 mmHg or more in all eyes but one (93% reduction).There were no significant complications.      

Conclusion

SLT seems to be an safe, effective and simple method of treating eyes with PACG when a sufficient extent of the angle are visible.     

Note from the Authors: No financial interest with Ellex

 

SLT for PACG Multicentre Study