Study title |
A randomized prospective study to determine the optimum power setting of SLT |
Type |
Randomized prospective |
Number of patients |
60 |
Primery investigator |
Madhu Nagar & David O’Brart |
Secondary investigators |
Dr A Kulkarni |
Contact informaion |
madhunagar@hotmail.com |
Place |
Clayton eye center & St Thomas |
Town |
Wakefield & London |
Country |
England |
Start date |
2005 |
Expected completion date |
2006 |
Expected publication date |
|
Purpose |
At the present time, although SLT is accepted as a viable treatment for OHT (Ocular Hypertension) / OAG (Open Angle Glaucoma), there has not been a thorough assessment of the optimum Laser power settings which enable safe and effective treatment. This study aims to scientifically compare high power settings with low power settings, investigating the efficacy of treatment in lowering intraocular pressure during the follow-up period after treatment, and the incidence of adverse events related to Laser treatment.
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method |
Research participants are to be recruited from the NHS glaucoma clinic at Clayton Hospital starting Jan 2006. Eligible participants will be patients with OHT or OAG, which is uncontrolled despite maximal tolerated medical therapy. We aim to recruit 40 patients. Each patient will be randomized to treatment to one eye with the Laserex Tango Laser in one of two treatment groups: Group I will receive high-energy SLT (1.2mJ shots) in the eye to be treated; Group II will receive low-energy SLT (0.6mJ shots) in the eye to be treated. Thus, 20 patients will be allocated to each group, with 40 patients in total.
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Preliminary Results |
Mean IOP, Significantly lower:
Success rates at 3 months:
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Conclusion |
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